FORMERLY PRO GAD ENHANCER

When GABA

runs low.

Many people carry a GAD1 variant that limits GABA production. Neuro Calm & Rebalance feeds the pathway five different ways — glycine, L-theanine, magnesium, zinc, and kava — to restore the brake the nervous system needs.

Shop Neuro Calm & Rebalance View Formula →

PROFESSIONAL GRADE · 60 CAPSULES · L-GLYCINE · L-THEANINE · KAVA

Neuro Calm & Rebalance bottle
INHIBITORY TONE
500 mg L-Glycine per serving

The other inhibitory signal.

Glycine is GABA's partner at the inhibitory receptor — at 500 mg it supports the calming half of the nervous system. Patients who don't respond to GABA supplements often respond here.

KAVA
150 mg Kava Kava Root

Traditional calm, measured.

Kavalactones bind GABA-A receptors directly, producing the calm that traditional Pacific practice has relied on for centuries. Dose is capped at a practitioner-safe level with clear use guidance.

DAILY DOSE
2 capsules, AM or PM

One dose, flexible timing.

Take two capsules in the morning or evening, 30 minutes from food. Do not exceed two capsules daily or use with alcohol. Review kava cautions with your practitioner.

MAY BENEFIT

Calm is
a cofactor problem.

01
GABA tone
Five ingredients feed the inhibitory pathway from precursor, receptor, and cofactor angles.
02
Nervous system balance
Magnesium orotate and zinc picolinate are core cofactors in GAD enzyme activity.
03
Sleep quality
Evening dosing supports the inhibitory tone required for sleep onset and maintenance.
04
Acute stress response
L-Theanine and kava blunt the sympathetic overshoot that arrives with acute stressors.
05
Focus under pressure
Glycine and theanine together produce calm alertness — steady without the jitters.
06
Non-responder support
Designed for patients who feel little or nothing from oral GABA alone.

Formula

Five ingredients. GABA support from multiple angles.

KEY INGREDIENTS

Magnesium
as Magnesium Orotate · 35 mg · 8% DV
Zinc
as Zinc Picolinate · 10 mg · 91% DV
L-Glycine
500 mg
L-Theanine
300 mg
Kava Kava Root
Piper methysticum · 150 mg

OTHER INGREDIENTS

Hypromellose (capsule), microcrystalline cellulose, ascorbyl palmitate, silicon dioxide.

DIRECTIONS

Adults: Adults take two capsules in the morning OR evening 30 minutes before or after a meal. Do not exceed more than two capsules daily or discuss with your healthcare practitioner for further guidance.

Neuro Calm & Rebalance supplement facts
MAY BENEFIT:
Sleep
Stress
Mood & Relaxation

Questions

Frequently asked.

Why does oral GABA fail for some people?
Oral GABA struggles to cross the blood-brain barrier in meaningful amounts. This formula instead feeds the pathway with precursors (glycine), receptor-active botanicals (kava, theanine), and enzyme cofactors (magnesium, zinc) — reaching the same downstream calm through more reliable routes.
Who is this formula for?
Adults with stress, sleep, or mood complaints who don't respond to GABA supplements directly, or those with suspected GAD1/GABA-pathway genetic variants. Practitioners also reach for it when anxiety, insomnia, or muscle tension track with methylation or mineral status issues.
Is kava safe?
At the practitioner-set dose in this formula, kava has a strong traditional and clinical safety record. The FDA has advised caution about high-dose kava and liver health — talk with your practitioner if you have liver disease, drink alcohol regularly, or take medications affecting the liver.
When should I take it?
Adults take two capsules either in the morning or the evening, 30 minutes before or after a meal. Do not exceed two capsules in a 24-hour period. Most patients pick one time window and stay consistent.
Can I drink alcohol while taking this?
No. Do not combine with alcohol or with other sedating medications — kava and alcohol share liver-metabolism pathways and can amplify drowsiness.
Is it safe during pregnancy?
No — do not use if you are pregnant or breastfeeding. Kava specifically is not recommended in those windows.

The Science

Learn the why.

methylation

How methylation shapes mood, focus, and energy

Mood, focus, and energy aren't separate systems — they run on the same methyl groups. Here's how the methylation cycle underwrites neurotransmitter chemistry, mitochondrial output, and the difference between a good day and a flat one.

Apr 4, 2026 →

hormones

COMT polymorphisms and stress: the "warrior vs worrier" gene

COMT clears dopamine and norepinephrine from your prefrontal cortex. One common polymorphism changes the speed — and shapes how you perform under stress. Here's what the research shows.

Apr 2, 2026 →

sleep

Methylation and sleep: how the methyl cycle shapes your night

Your ability to fall asleep, stay asleep, and recover overnight is partly a methylation problem. Here's how the methyl cycle connects to circadian rhythm, melatonin production, and the chemistry of restorative sleep.

Feb 21, 2026 →