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SLEEP & CIRCADIAN STACK

Quiet the mind,

reset the night.

A two-product protocol that pairs a calming neurotransmitter blend with circadian-timed micronutrients. Built for adults whose sleep quality, not just quantity, is the problem.

Shop Quality Sleep Bundle View Formula →

Purchases are completed at Neurobiologix, the seller. Gene Direct Nutrition may earn a commission.

PROFESSIONAL GRADE · 2 PRODUCT BUNDLE · GABA · MELATONIN · MAGNESIUM

Quality Sleep Bundle bottle
ARCHITECTURE
2 synergistic formulas

Two angles on the same problem.

Sleep is neurochemistry plus circadian timing. This bundle pairs a GABA-forward relaxation blend with nutrient cofactors that help the nervous system settle into deeper phases of the cycle.

CALM
PM dosing protocol

Engineered for the evening.

Both formulas are designed to be taken in the evening — layering inhibitory support (GABA, magnesium) with the micronutrient backbone the brain uses to wind down cleanly.

METABOLIC
GLUCOSE steady overnight

Blood sugar, while you sleep.

Blood sugar instability is a hidden driver of 3 a.m. wakeups. The stack includes ingredients that support steady nocturnal glucose — a foundation for uninterrupted sleep architecture.

MAY BENEFIT

Sleep is a
biology problem.

01
Sleep onset
Inhibitory neurotransmitter support helps quiet the chatter that keeps the brain awake.
02
Overnight blood sugar
Nutrient cofactors support steady glucose — reducing the stress spikes that fragment sleep.
03
Stress & nervous system
Magnesium and calming amino acids down-regulate a sympathetic-dominant evening state.
04
Memory & cognition
Deeper sleep is where memory consolidation happens — consistent rest supports next-day clarity.
05
Mood & relaxation
GABA-pathway support lowers the evening arousal that often tracks with anxious mood.
06
Daytime focus
Restored sleep architecture is the upstream lever for sustained attention and working memory.

Questions

Frequently asked.

What two products are in the Quality Sleep Bundle?
The bundle pairs two Neurobiologix sleep-targeted formulas designed to be used together in the evening. One addresses the relaxation and neurotransmitter side of sleep; the other supports overnight blood sugar and nervous-system settling. Follow the label directions on each product.
Who is this bundle designed for?
Adults who fall asleep fine but wake in the middle of the night, or whose sleep feels unrefreshing despite adequate hours. It is also useful for people with stress-related or blood-sugar-related sleep disruption. Work with a practitioner if you are on sleep or psychiatric medications.
When should I take it?
Both formulas are evening-dosed. Follow the label on each bottle — typically 30 to 60 minutes before bed. Consistency matters more than precise timing; the nervous system responds to a repeated evening signal.
Will it leave me groggy in the morning?
The formulas lean on nutritional cofactors and calming amino acids rather than heavy sedatives, so most people wake clear-headed. If you feel lingering grogginess, shift the dose earlier in the evening or step down to a partial dose.
Can I use it every night long-term?
Yes — these are nutrient and amino-acid formulas, not habit-forming sedatives. Many people use them as nightly foundational support, especially through high-stress seasons. Reassess periodically with a practitioner.
Is it safe during pregnancy or while breastfeeding?
Consult your healthcare practitioner before use if you are pregnant, lactating, or taking medications — particularly sleep aids, antidepressants, or blood-sugar medications.

The Science

Learn the why.

methylation

How methylation shapes mood, focus, and energy

Mood, focus, and energy aren't separate systems — they run on the same methyl groups. Here's how the methylation cycle underwrites neurotransmitter chemistry, mitochondrial output, and the difference between a good day and a flat one.

Apr 4, 2026 →

sleep

Methylation and sleep: how the methyl cycle shapes your night

Your ability to fall asleep, stay asleep, and recover overnight is partly a methylation problem. Here's how the methyl cycle connects to circadian rhythm, melatonin production, and the chemistry of restorative sleep.

Feb 21, 2026 →

sleep

Melatonin and MTHFR: the connection you weren't told about

The last step of melatonin synthesis is a methylation reaction — and the methyl group comes from the same cycle MTHFR drives. Here's the biochemistry connecting your sleep hormone to your folate genetics.

Feb 8, 2026 →

Weekly research note

Evidence-based methylation insights, delivered weekly.

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