BIOACTIVE B COMPLEX
Methylated B's,
done right.
A full B-complex built around the active forms — methylfolate, methylcobalamin, P-5-P, and benfotiamine. The cofactors your cells can actually use, paired to support energy, methylation, and nervous system function.
Purchases are completed at Neurobiologix, the seller. Gene Direct Nutrition may earn a commission.
PROFESSIONAL GRADE · 60 CAPSULES · METHYLFOLATE · METHYLCOBALAMIN · P-5-P
Active forms, not precursors.
Benfotiamine, riboflavin-5-phosphate, P-5-P, and 5-MTHF skip the conversion steps your genetics may stall at. This is a B-complex that works whether or not MTHFR is on your side.
The one-carbon pathway, fed.
Methylcobalamin and methylfolate team up to drive the methylation cycle — the chemistry behind DNA repair, neurotransmitter synthesis, and homocysteine balance.
Simple, once-daily support.
One capsule covers the full B-complex backbone. Pair with your morning meal for steady energy, stable mood, and methylation support from the start of the day.
MAY BENEFIT
Bioactive B's
for real biology.
Formula
Eight B vitamins in the forms your cells already recognize.
KEY INGREDIENTS
OTHER INGREDIENTS
Hydroxypropyl Methylcellulose, Water, Microcrystalline Cellulose, Silicon Dioxide, Ascorbyl Palmitate
DIRECTIONS
Adults: Take one capsule daily with food or as directed by a healthcare practitioner.
Questions
Frequently asked.
What makes this different from a standard B-complex?
Who benefits most from activated B vitamins?
Can I take it with other methylation products?
When should I take it?
Will it turn my urine bright yellow?
Is it safe during pregnancy?
The Science
Learn the why.
immune
Methylation and the immune system: how one cycle shapes inflammation
The methylation cycle is not just a mood and detox system — it quietly regulates how your immune cells turn on, turn off, and resolve inflammation. Here's the connection.
Mar 23, 2026 →nutrition
Homocysteine: what drives it up, what brings it down
Elevated homocysteine is one of the most actionable labs in functional medicine. Here's what pushes it up, what pulls it down, and how to interpret your number alongside genetics and symptoms.
Feb 26, 2026 →nutrition
P5P vs pyridoxine HCl: vitamin B6 forms, conversion, and safety
P5P and pyridoxine HCl both supply vitamin B6, but they enter the B6 pathway differently. Compare their metabolism, labels, testing, doses, and neuropathy risk.
Apr 14, 2026 →