FORMERLY NIGHTTIME CALMING COMPLEX
Serotonin, GABA,
then sleep.
A physician-formulated stack of seven ingredients that feed the chemistry of restorative sleep — valerian, passionflower, chamomile, GABA, L-theanine, and melatonin working in one capsule.
Purchases are completed at Neurobiologix, the seller. Gene Direct Nutrition may earn a commission.
PROFESSIONAL GRADE · 60 CAPSULES · VALERIAN · GABA · L-THEANINE · MELATONIN

The full wind-down stack.
Standardized valerian, passionflower, and chamomile support GABA tone. L-Theanine shifts brain waves toward alpha. Melatonin cues the circadian signal. One capsule covers the whole pathway.
Circadian rhythm, restored.
A targeted 3 mg dose of melatonin nudges the sleep-wake cycle without the grogginess of higher doses. Backed by GABA and 100 mg L-Theanine for a smooth transition into deep sleep.
Take an hour before sleep.
Adults take 1-2 capsules one hour before bedtime. Children 90+ lbs take one capsule. Not for use with alcohol or machinery operation — this formula is designed to bring sleep, not wakefulness.
MAY BENEFIT
Sleep is a
chemistry problem.
Formula
Seven ingredients. Every one tied to sleep physiology.
KEY INGREDIENTS
OTHER INGREDIENTS
Hypromellose (capsule), microcrystalline cellulose, ascorbyl palmitate, silicon dioxide.
DIRECTIONS
Adults: As a dietary supplement, adults take one-to-two capsules one hour before bedtime or as directed by a healthcare professional. For children 90 pounds and above, take one capsule one hour before bedtime.

Questions
Frequently asked.
Will I feel groggy the next morning?
How is this different from melatonin alone?
Can children take it?
Can I take it with medication?
Is it habit-forming?
Is it safe during pregnancy or breastfeeding?
The Science
Learn the why.
methylation
How methylation shapes mood, focus, and energy
Mood, focus, and energy aren't separate systems — they run on the same methyl groups. Here's how the methylation cycle underwrites neurotransmitter chemistry, mitochondrial output, and the difference between a good day and a flat one.
Apr 4, 2026 →sleep
Methylation and sleep: how the methyl cycle shapes your night
Your ability to fall asleep, stay asleep, and recover overnight is partly a methylation problem. Here's how the methyl cycle connects to circadian rhythm, melatonin production, and the chemistry of restorative sleep.
Feb 21, 2026 →sleep
Melatonin and MTHFR: the connection you weren't told about
The last step of melatonin synthesis is a methylation reaction — and the methyl group comes from the same cycle MTHFR drives. Here's the biochemistry connecting your sleep hormone to your folate genetics.
Feb 8, 2026 →