FORMERLY GLUTATHIONE TOPICAL PRO

Glutathione,

through the skin.

Transdermal L-glutathione in a liposomal base — 50 mg per pump, delivered directly through the skin to skip the gut entirely. Paired with methylated B-vitamins and essential oils for a full detox-support topical.

Shop Glutathione Topical View Formula →

PROFESSIONAL GRADE · 70 PUMPS · L-GLUTATHIONE · METHYLFOLATE · B12

Glutathione Topical bottle
DELIVERY
50 mg glutathione per pump

Bypass the gut entirely.

Oral glutathione is largely destroyed in digestion. A transdermal liposomal base with medium-chain triglycerides and lecithin carries reduced glutathione across the skin — the rare form of delivery that preserves the molecule.

METHYLATION
3 B-vitamin cofactors

Niacin, methylfolate, methyl B12.

Glutathione metabolism depends on methylation. This formula adds L-methylfolate (5-MTHF), methylcobalamin, and niacin — the B-vitamins that keep one-carbon chemistry moving, even in MTHFR patients.

AROMATHERAPY
6 essential oils in the base

Lavender, rosewood, geranium, more.

A blend of orange, lavender, geranium, rosewood, frankincense, and rose absolute oils gives the cream a mood-lifting scent while staying clean enough for daily use on thin-skin areas.

MAY BENEFIT

Detox isn't optional
when toxins aren't.

01
Cellular antioxidant defense
Glutathione is the master intracellular antioxidant, scavenging free radicals and recycling other antioxidants.
02
Heavy metal processing
Glutathione conjugates mercury, cadmium, lead, and other metals into water-soluble forms for excretion.
03
Xenobiotic clearance
Supports Phase II liver conjugation of PCBs, synthetic estrogens, and environmental contaminants.
04
Immune tone
Adequate glutathione is associated with balanced lymphocyte function and resilience under viral load.
05
Methylation partnership
Added L-methylfolate, methyl B12, and niacin support the one-carbon chemistry that regulates glutathione recycling.
06
GI bypass
Transdermal delivery avoids the gut entirely — useful for patients with absorption issues or sensitive digestion.

Formula

Liposomal transdermal glutathione with methylated B-vitamin support.

KEY INGREDIENTS

Water
Reverse Osmosis
Medium-Chain Triglycerides
L-Glutathione Reduced
Polyacrylamide
C13-14 Isoparaffin
Laureth-7
Ethanol
Lecithin
Glycerin
Sodium Hydroxymethylglycinate
Glucosamine Sulfate
L-Carnosine
Xanthan Gum
Fragrance
Vitamin E
D-Alpha Tocopherol
Potassium Sorbate
Sodium Phytate
Orange Essential Oil
Lavender Essential Oil
Geranium Essential Oil
Rosewood Essential Oil
Frankincense Essential Oil
Rose Absolute Oil
Niacin
Vitamin B-3
Folate
As L-Methyltetrahydrofolate
Vitamin B12
As Methylcobalamin

OTHER INGREDIENTS

Water (reverse osmosis), medium chain triglycerides, L-Glutathione reduced, polyacrylamide (and) C-13-14 isoparaffin (and) laureth-7, ethanol, lecithin (from sunflower), glycerin, sodium hydroxymethylglycinate, glucosamine sulfate, L-Carnosine, xanthan gum, natural fragrance, vitamin E (d-alpha tocopherol), potassium sorbate, sodium phytate, orange essential oil, lavender essential oil, geranium essential oil, rosewood essential oil, frankincense essential oil, rose absolute oil, niacin (vitamin B-3), folate (as L-methyltetrahydrofolate), vitamin B-12 (as methylcobalamin).

DIRECTIONS

Adults: For children ages 2-11, use one-half to one pump. For children ages 12 and older, use one-to-two pumps daily. Apply the topical cream directly over the liver or abdomen or a thin skin area without hair.

Glutathione Topical supplement facts
MAY BENEFIT:
Cardiovascular Health
Detoxification
Healthy Aging
Liver Health
Inflammation
Immune System

Questions

Frequently asked.

Why transdermal instead of oral or liposomal oral?
Oral glutathione is largely hydrolyzed in the stomach; only a fraction reaches circulation intact. A well-formulated transdermal cream bypasses the gut entirely, crossing the skin via the liposomal base. For patients with GI issues, MTHFR methylation weakness, or absorption challenges, this is often the most reliable delivery.
Where should I apply it?
Apply the cream directly over the liver (right upper abdomen), the inner forearm, or any thin-skin area without hair. Rotate sites to avoid local saturation. Let the cream absorb for a few minutes before covering with clothing.
Why are B-vitamins in a glutathione cream?
Glutathione is recycled in the cell through a pathway that depends on methylation. Adding niacin, L-methylfolate, and methylcobalamin means the supporting chemistry is present alongside the glutathione itself, which is especially useful for MTHFR patients.
Can children use it?
Yes — the label allows 1/2 to 1 pump for children ages 2–11 and 1–2 pumps for kids 12 and older. Apply over the liver or abdomen. Work with a pediatric or integrative practitioner for dosing guidance.
Will I smell like essential oils?
There is a noticeable but pleasant scent from the orange, lavender, geranium, rosewood, frankincense, and rose absolute blend. The fragrance fades as the cream absorbs.
Is it safe during pregnancy or breastfeeding?
Consult your healthcare provider before use if pregnant, lactating, or taking medications. Some of the essential oils and methylated B-vitamins warrant oversight during pregnancy.

The Science

Learn the why.

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Methylation and the immune system: how one cycle shapes inflammation

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Feb 26, 2026 →

mthfr

MTHFR and homocysteine: the connection that actually matters

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Feb 23, 2026 →